• Lina Mardiana Department of Chemistry, FMIPA, Universitas Indonesia, 16424, Depok, Indonesia
  • Bayu Ardiansah Department of Chemistry, FMIPA, Universitas Indonesia, 16424, Depok, Indonesia http://orcid.org/0000-0002-1664-9133
  • Ridla Bakri Department of Chemistry, FMIPA, Universitas Indonesia, 16424, Depok, Indonesia
  • Antonius Herry Cahyana Department of Chemistry, FMIPA, Universitas Indonesia, 16424, Depok, Indonesia
  • Yulia Anita Research Center for Chemistry (RC-Chem), Indonesian Institute of Sciences (LIPI), 15314, Tangerang, Indonesia
  • Nuraini Pahlawati Aziza Department of Chemistry, FMIPA, Universitas Indonesia, 16424, Depok, Indonesia




Activated chicken eggshells, chalcones, Aldol condensation


A simple preparation of sodium impregnated on activated chicken eggshells (Na-ACE) as a solid base material for substituted chalcones synthesis is presented. After characterization using FTIR, XRD, SEM, EDS and total basicity, the catalyst was applied in Aldol condensation to produce corresponding chalcones 3a-3j. Confirmation of products structure has been done by FTIR, UV-Vis and MS instruments. Reaction can be carried out in relative short time with ethanol as the best solvent and gave the highest yield of 95 %. This research presented a facile synthesis of chalcone derivatives, the prominent class of organic compounds with interesting biological activities. 


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