ANTIOXIDANT ACTIVITY OF LEAF EXTRACTS OF GLOBIMETULA BRAUNII (ENGLER) VAN TIEGH PARASITIZING ON PILIOSTIGMA THONNINGII AND PARKIA BIGLOBOSA
DOI:
https://doi.org/10.11113/jt.v79.10574Keywords:
Globimetula braunii, Piliostigma thonningii, Parkia biglobosa, FRAP, ABTS, DPPHAbstract
The dried leaves of Globimetula braunii parasitizing on Piliostigma thonningii and Parkia biglobosa were successively extracted using n-hexane, dichloromethane, ethyl acetate and methanol by cold extraction method. All the extracts were evaluated for antioxidant activities using FRAP, ABTS and DPPH assays. The MeOH extract of G. braunii parasitizing on P. thonningii displayed the highest DPPH scavenging activity with SC50 value 2.82 µg/mL while the EtOAc extract of G. braunii parasitizing on P. biglobosa showed highest antioxidant scavenging capacity in the ABTS assay with SC50 value of 138.9 µg/mL. The MeOH extract of G. braunii parasitizing on P. biglobosa showed the highest FRAP equivalent value of 9.68 ± 0.14 mM. These results showed that EtOAc and MeOH are suitable solvents for extraction of active antioxidant agents from the leaves of G. braunii parasitizing on both hosts.
References
Scheibmeir, H. D., Christensen, K., Whitaker, S. H., Jegaethesan, J., Clancy, R. and Pierce, J. D. 2005. A Review of Free Radicals and Antioxidants for Critical Care Nurses. Intensive and Critical Care Nursing. 21(1): 24-28.
Velioglu, Y. S., Mazza, G., Gao, L. and Oomah, B. D. 1998. Antioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products. Journal of Agricultural Food Chemistry. 46(10): 4113-4117.
Da Silva, M. C. and Paiva, S. R. 2012. Antioxidant Activity and Flavonoid Content of Clusia fluminensis Planch. and Triana. Annals of the Brazilian Academy of Sciences. 84(3): 609-616.
Argolo, A. C. C., Sant’Ana, A. E. G., Pletsch, M. and Coelho, L. C. B. B. 2004. Antioxidant Activity of Leaf Extracts from Bauhinia monandra. Bioresource Technology. 95(2): 229-233.
Ebrahimzadeh, M. A., Pourmorad, F. and Hafezi, S. 2008. Antioxidant Activities of Iranian Corn Silk. Turkish Journal of Biology. 32: 43-49.
Gulcin, I., Topal, F., Sarikaya, S. B. O., Bursal, E., Bilsel, G. and Goren, A. C. 2011. Polyphenol Content and Antioxidant Properties of Medler (Mespilus germanica L.). Records of Natural Products. 5(3): 158-175.
Johnrii, M. 1987. Tropical Mistletoes. In Weber, H. C. Forstreuter, W. (Eds.). Proceedings of the Fourth International Symposium on Parasitic Flowering Plants, Marburg, Germany. 250-252.
Tizhe, T. D., Alonge, S. O. and Aliyu R. E. 2015. Antibacterial Activity of Globimetula braunii Sourced from Five Different Host Trees in Samaru, Zaria, Nigeria. International Journal of Current Science. 18: 117-123.
Al-Ghaithi F, Mandouh R., El-Ridi M.R., Adeghate E., Amiri M. H. 2004. Biochemical Effect of citrullus colocynthis in Normal and Diabetic rats. Molecular and Cellular Biochemistry. 261: 143-149.
Olagunju, J. A., Ismail, F. I. and Gbile. Z. O. 1999. The Hypoglycaemic Property of Normal Saline Leaf of Globimetula braunii in Alloxanised Diabetic Albino Rats. Biomedical Letter. 60(235): 83-89.
Ouedraogo, S., Ranaivo, H. R., Ndiaye, M., Kabore, Z. I., Guissou, P. I and Bucher, B. 2004. Cardiovascular Properties of Aqueous Extract from Mitragyna inermis (Wild). Journal Ethnopharmacology. 93: 345-50.
Musa, M. A., Abdullahi, I. M., Muhammad, K. J. and Magaji, G. M. 2014. Phytochemical Screening and Anticonvulsant Studies of Ethyl Acetate Fraction of Globimetula braunii on Laboratory Animals. Asian Pacific Journal of Tropical Biomedicine. 4(4): 285-289.
Okpuzor, J., Ogbunugafor, H. A. and Kareem, G. K. 2009. Hepatic and Hematologic Effects of Fractions of Globimetula braunii in Normal Albino Rats. Experimental and Clinical Sciences International Journal. 8: 182-189.
Adewumi, A. A. J., Aina, V. O., Alhassan, S. and Adebayo, F. I. 2011. Antibacterial Activity of Globimetulla browni (Mistletoe) Leaf Extract Against Four Clinical Bacterial Isolates. Journal of Pharmaceutical and Allied Sciences. 8(3): 1355-1361.
Oboh, I. E. and Nworgu, Z. A. M. 2008. Oxytocic Properties of the Aqueous Extract of Globimetulla braunii (Loranthaceae). Pakistan Journal of Pharmaceutical Science. 21(4): 356-360.
Najihah, M. H., Mawardi, R., Ee, G. C. L., Mohd, A. S., Maizatulakmal. Y., Muhammad, A. M. A., Abd, M. A. and Go, G. 2012. Antioxidant, antimicrobial and Tyrosinase Inhibitiry Activities of Xanthones Isolated from Artocarpus obtusus F. M. Jarret. Molecules. 17: 6071-6082.
Zou, Y., Chang, S. K. C., Gu, Y. and Qian, S. Y. 2011. Antioxidant Activity and Phenolic Composition of Lentils (Lens Culinaris var. Morton) Extracts and its Fractions. Journal of Agricultural Food Chemistry. 59(6): 2268-2276.
Channarong, A., Jutiviboonsuk, A. and Korsanan, S. 2012. Total Reducing Antioxidant Capacity of Thai Herbal Aromatic Powder (Ya-Hom) Measured by FRAP Assay. Thai Pharmaceutical and Health Science Journal. 7(3): 111-114.
Shahwar, D., Raza, M. A., Bukhari, S. and Bukhari, G. 2012.Ferric Reducing Antioxidant Power of Essential Oils Extracted from Eucalyptus and Curcuma Species. Asian Pacific Journal of Tropic Biomedicine. S1633-S1636.
Seladji, M., Bekhechi, C., Beddou, F., Dib, H. and Bendimerad, N. 2014. Antioxidant Activity and Phytochemical Screening of Nepeta nepetella aqueous and methanolic extracts from Algeria. Journal of Applied Pharmaceutical Science. 4(2): 012-016.
Turker, A. U. and Usta, C. 2008. Biological Screening of Some Turkish Medicinal Plants for Antimicrobial and Toxicity Studies. Natural Product Research. 22: 136-146.
Oyedemi, S. O. and Afolayan, A. J. 2011. In Vitro and in Vivo Antioxidant Activity of Aqueous Leaves Extract of Leonotis leonurus (L.) R.Br. International Journal Pharmacology. 7: 248-256.
Luciana, L. M., Fa Ìbio, S. M., Gilda, G. L., Alexandre, S. R., Tereza, C. S., Cintia, S. C. and Suzana, G. L. 2001. Screening of Brazilian Plant Extracts for Antioxidant Activity by the Use of DPPH Free Radical Method. Phytotherapy Research.15:127-130.
Alabri, T. H. A., Al Musalami, A. H. S., Hossain, M. A., Weli, A. M. and Al-Riyami, Q. 2014. Comparative Study of Phytochemical Screening, Antioxidant and Antimicrobial Capacities of Fresh and Dry Leaves Crude Plant Extracts of Datura metel L. Journal of King Saud University Science. 26: 237-243.
Rice-Evans, C. A., Miller, N. J. and Paganga, G. 1996. Structure Antioxidant Activity Relationships of Flavonoids and Phenolic Acids. Free Radical Biology Medicine. 20: 933-956.
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