EVALUATION OF ANTIOXIDANT, ANTIMICROBIAL AND WOUND HEALING ACTIVITY OF POIKILOSPERMUM SUAVEOLENS

Authors

  • Hartati Ahmad Biology Department, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, 90224, Makassar, Indonesia https://orcid.org/0000-0001-7139-9061
  • Muhammad Habil Ahmad Biology Department, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, 90224, Makassar, Indonesia
  • Alimuddin Ali Biology Department, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, 90224, Makassar, Indonesia
  • Halifah Pagarra Biology Department, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, 90224, Makassar, Indonesia https://orcid.org/0000-0001-6483-8513
  • Pince Salempa Chemistry Department, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, 90224, Makassar, Indonesia
  • Liza Md Salleh Bioprocess Engineering of Department, Faculty of Chemical Engineering, Universiti Teknology Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia https://orcid.org/0000-0001-8674-0840
  • Muharram Passitta Chemistry Department, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, 90224, Makassar, Indonesia

DOI:

https://doi.org/10.11113/jurnalteknologi.v84.16858

Keywords:

Antimicrobial, Antioxidant, wound healing activity, Poikilospermum suaveolens

Abstract

Poikilospermum suaveolens is a plant could grows in the limestone area in Maros, Indonesia. The leaves are generally widely used as traditional medicine for treatment of wounds by local communities. This study aims to examine the wound healing potential of P. suaveolens leaves extract as well as scientific clarify of the plant. The plant leaves were extracted by maceration. The measurement of antioxidant activity by the DPPH technique (1,1 diphenil-2-pikrilhidrazil) spectrophotometrically. The antimicrobial activity was evaluated by formation of the inhibition zone. The wound healing activity was performed the percentage of injury closure in rats skin injury. The antioxidant activity showed that 70% ethanol and ethyl acetate extracts were not significantly different, however, highly distinct to the positive control (Butylated Hidroxyanisole). The antimicrobial activity of extract showed 70% ethanol and ethyl acetate extracts were not significantly against Staphylococcus aureus and Candida albicans, but significantly against Pseudomonas aeruginosa. The evaluation of P. suaveolens extract on the rate of wound closure activity quickly, i.e., within 15 days the injury on the test animal was recovered. This study concludes that the P. suaveolens plant extracts are potential as a sources of active substances for wound healing.

Author Biography

Muhammad Habil Ahmad, Biology Department, Faculty of Mathematics and Natural Science, Universitas Negeri Makassar, 90224, Makassar, Indonesia

Biology of Department

Published

2021-11-21

How to Cite

Ahmad, H., Ahmad, M. H., Ali, A., Pagarra, H., Salempa, P., Md Salleh, L., & Passitta, M. (2021). EVALUATION OF ANTIOXIDANT, ANTIMICROBIAL AND WOUND HEALING ACTIVITY OF POIKILOSPERMUM SUAVEOLENS. Jurnal Teknologi, 84(1). https://doi.org/10.11113/jurnalteknologi.v84.16858

Issue

Section

Science and Engineering