Development of HPLC Fingerprint Analysis of Traditional Diabetes Herbal Jamu Diabetes Plant Materials

Authors

  • Gholamhossein Shams Department of Chemical Engineering, Arak branch, Islamic Azad University, Arak, Iran
  • Hassan Fahmi Ismail Tissue Culture Engineering Laboratory, Department of Bioprocess Engineering, Faculty of Chemical Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia
  • Teh Liam Chee Tissue Culture Engineering Laboratory, Department of Bioprocess Engineering, Faculty of Chemical Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia
  • M Abbas Ali Department of Bioprocess Engineering Faculty of Chemical Engineering Universiti Teknologi Malaysia, 81310 UTM Skudai, Johor, Malaysia
  • Fadzilah Adibah Abdul Majid Tissue Culture Engineering Laboratory, Department of Bioprocess Engineering, Faculty of Chemical Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia
  • Mohamad Roji Sarmidi Institute of Bioproduct Development, Faculty of Chemical Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia
  • Ramlan Abdul Aziz Institute of Bioproduct Development, Faculty of Chemical Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia

DOI:

https://doi.org/10.11113/jt.v68.1686

Keywords:

Jamu diabetes, HPLC, fingerprint, bioactive markers

Abstract

Selective and efficient analytical methods are required not only for quality assurance but also for authentication of herbal formulations. In the present study, high-performance liquid chromatography (HPLC) detection was developed for chromatographic fingerprint analysis of the extract from grounded plant materials of Jamu Diabetes (JD), a well known herbal formulation in Malaysia. The bioactive markers rosmarinic acid, curcumin, cinnamaldehyde and andrographolide were identified from the methanol/water (80:20) extract of JD materials. The data presented in this study showed that the developed method is simple, sensitive and specific for simultaneous determination of the indicated marker compounds either qualitatively or quantitatively, and may be used as a fingerprint profile for the standardization of extractives or herbal medicines from herbal formulation JD materials.

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Published

2014-04-22

Issue

Vol. 68 No. 1: May 2014

Section

Science and Engineering

License

Copyright of articles that appear in Jurnal Teknologi belongs exclusively to Penerbit Universiti Teknologi Malaysia (Penerbit UTM Press). This copyright covers the rights to reproduce the article, including reprints, electronic reproductions, or any other reproductions of similar nature.

How to Cite

Development of HPLC Fingerprint Analysis of Traditional Diabetes Herbal Jamu Diabetes Plant Materials. (2014). Jurnal Teknologi, 68(1). https://doi.org/10.11113/jt.v68.1686