Numerical Modeling of Blood Flow in Irregular Stenosed Artery with the Effects of Gravity

Authors

  • Tan Yan Bin Department of Mathematical Sciences, Faculty of Science, UniversitiTeknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia
  • Norzieha Mustapha Department of Mathematical Sciences, Faculty of Science, UniversitiTeknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia

DOI:

https://doi.org/10.11113/jt.v62.1889

Keywords:

Blood flow, gravity, irregular stenosis, Newtonian fluid, MAC method

Abstract

A numerical study on the influences of gravitational force on an unsteady two–dimensional nonlinear model of blood flow through a stenosed artery is presented. Blood flow through the constricted region with an irregular stenosis is considered as incompressible Newtonian fluid. The governing equations are derived from the Navier–Stokes equations, which also comprise a significant term for gravitational force in the axial momentum equation. The numerical method chosen in this study is the finite difference approximations based on Marker and Cell (MAC) method at which governing equations are develop in staggered grids for discretization. The Poisson equation of pressure is solved by successive–over–relaxation (S.O.R.) method. Pressure–velocity corrector is imposed to increase accuracy. Streamlines, wall shear stress and axial velocity profiles are plotted.

References

Ku, D. N. 1997. Blood Flow in Arteries. Annu. Rev. Fluid Mechanics. 29: 399–434.

Mandal, P. K., Chakravarty, S., Mandal, A., and Amin, N. 2007. Effect of Body Acceleration on Unsteady Pulsatile Flow of Non-Newtonian Fluid through a Stenosed Artery. Applied Mathematics and Computation. 189: 766–779.

Ling, S. C., & Atabek, H. B. 1972. A Nonlinear Analysis of Pulsatile Flow in Arteries. J. Fluid. Mech. 55: 493–511.

Padmanabhan, N. 1980. Mathematical Model of Arterial Stenosis. Med. & Biol. Eng. & Comput. 18: 281–286.

Back, L. H., Cho, Y. I., Crawford, D. W. and Cuffel, R. F. Effect of mild atherosclerosis on flow resistance in a coronary artery casting of man. ASME J. Biomech. Eng. 1984. 106: 48–53.

Johnston, P. R. and Kilpatrick, D. 1991. Mathematical modelling of flow through an irregular arterial stenosis. J. Biomech. 24: 1069–1077.

Chakravarty, S. and Sannigrahi, A. K. 1994. Effects of body acceleration on Blood Flow in an Irregular Stenosed Artery. Mathl. Comput. Modelling. 19(5): 93–103.

Jung, H., Choi, J. W., and Park, C. G. 2004. Asymmetric Flows of Non-Newtonian Fluids in Symmetric Stenosed Artery. Korea-Australia Rheology Journal. 16(2): 101–108.

Mandal, P. K. 2005. An Unsteady Analysis of Non-Newtonian Blood Flow through Tapered Arteries with a Stenosis. International Journal of Non-Linear Mechanics. 40: 151–164.

Mustapha, N., Chakravarty, S., Mandal, P. K., & Amin, N. 2008. Unsteady Response of Blood Flow through a Couple of Irregular Arterial Constrictions to Body Acceleration. Journal of Mechanics in Medicine and Biology. 8(3): 395–420.

Mustapha, N., Amin, N., Chakravarty, S., and Mandal, P. K. 2009. Unsteady Magnetohydrodynamic Blood Flow Through Irregular Multi-stenosed Arteries. Computers in Biology and Medicine. 39: 896–906.

Mustapha, N., Mandal, P. K., Johnston, P. R., and Amin, N. A. 2010. Numerical Simulation of Unsteady Blood Flow Through Multi-Irregular Arterial Stenoses. Applied Mathematical Modelling. 34: 1559–1573.

Kim, C. S., Kiris, C., Kwak, D. and David, T. 2006. Numerical Simulation of Local Blood Flow in the Carotid and Cerebral Arteries under Altered Gravity. Journal of Biomechanical Engineering. 128: 194–202.

Payne, S. J. 2004. Analysis of the Effects of Gravity and Wall Thickness in a Model of Blood Flow Through Axisymmetric Vessels. Medical & Biological Engineering & Computing. 42: 799–806.

Burrowes, K. S., Hunter, P. J. and Tawhai, M. H. 2005. Investigation of the Relative Effects of Vascular Branching Structure and Gravity on Pulmonary Arterial Blood Flow Heterogeneity via an Image-based Computational Model. Academic Radiology. 12(11): 1464–1474.

Burrowes, K. S. and Tawhai, M. H. 2006. Computational Predictions of Pulmonary Blood Flow Gradients: Gravity Versus Structure. Respiratory Physiology & Neurobiology. 154: 515–523.

Boynton, R. 2001. Precise Measurement of Mass.

Heusden, K., Gisolf, J., Stok, W. J., Dijkstra, S., and Karemaker, J. M. 2006. Mahtematical Modeling of Gravitational Effects on the Circulation: Importance of the Time Course of Venous Pooling and Blood Volume Changes in the Lungs. AJP – Heart and Circulatory Physiology. 291: H2152-H2165.

Olufsen, M. S., Smith, B., Mehlsen, J. and Ottesen, J. 2011. The impact of gravity during head-up tilt. 33rd Annual International Conference if the IEEE EMBS.

Chakravarty, S. and Mandal, P. K. 1996. A Nonlinear Two-Dimensional Model of Blood Flow in an Overlapping Arterial Stenosis Subjected to Body Acceleration. Mathl. Comput. Modelling. 24(1): 43–58.

Rappitsch, G. and Perktold, K. 1996. Computer simulation of convective diffusion processes in large arteries. J. Biomech. Eng. 124: 1–8.

Stangeby, D. K. and Eithier, C. R. 2002. Computational Analysis of Coupled Blood Wall Arterial LDL Transport. J. Biomech Eng. 124: 1–8.

Tu, C., Deville, M., Dheur, L. and Vanderschuren, L. 1992. Finite Element Simulation of Pulsatile Flow Through Arterial Stenosis. J. Biomech. 25: 1141–1152.

Harlow, F. H. and Welch, J. E. 1965. Numerical Calculation of Time-dependent Viscous Incompressible Flow of Fluid with Free Surface. Phys. Fluids. 8(12): 2182–2189.

Midya, C., Layek, G. C., Gupta, A. S. and Mahapatra, T. R. 2003. Magnetohydrodynamic Viscous Flow Separation in a Channel with Constrictions. ASME J. Fluids Engng. 125: 952–962.

Markham, G. and Proctor, M. V. 1983. C.E.G.B. Report TRPD/L/0063/M82.

Welch, J. E., Harlow, F. H., Shannon, J. P. and Daly, B. J. 1996. The MAC method. Los Alamos Scientific Lab, Report LA-3425, Los Alamos. 1996.

Hirt, C. W. 1968. Heuristic stability theory for finite difference equations. J. Comput. Phys. 2: 339.

Downloads

Published

2013-05-15

Issue

Section

Science and Engineering

How to Cite

Numerical Modeling of Blood Flow in Irregular Stenosed Artery with the Effects of Gravity. (2013). Jurnal Teknologi (Sciences & Engineering), 62(3). https://doi.org/10.11113/jt.v62.1889