Antioxidant Activity and Total Phenolic Contents in Methanol Extracts from Swietenia Mahagoni and Andrographis Paniculata
DOI:
https://doi.org/10.11113/jt.v69.3173Keywords:
Antioxidant, total phenolic contents, methanol extracts, Swietenia mahagoni, Andrographis paniculataAbstract
Traditional medicinal plants such as Swietenia mahagoni and Andrographis paniculata are rich with bioactive compounds. The phenolic composition and antioxidant activity of methanol extract from Swietenia mahagoni and Andrographis paniculata were studied. They were extracted by Soxhlet extraction of 70% methanol solvent. The results obtained from this study showed Andrographis paniculata gave highest percentage yield by 19.94% compared to Swietenia mahagoni at 11.86%. In antioxidant activity, Andrographis paniculata and Swietenia mahagoni showed 89.93% and 60.77% respectively. While for total phenolic content highest in extract of Swietenia mahagoni by 55.0 mg/g and Andrographis paniculata only 7.7 mg/g.
References
Chen, Y. Y., X. N. Wang, C. Q. Fan, S. Yin and J. M. Yue. 2007. Swiemahogins A and B, Two Novel Limnoids from Swietenia mahogany. Tetrahedron Letters. 48: 7480–7484.
Bacsal, K., L. Chavez, I. Diaz, S. Espina, J. Javillo, H. Manzanilla, J. Motalban, C. Panganiban, A. Rodriguez, C. Sumpaico and B. Talip and S. Yap. 1997. The Effect of Swietenia mahagoni (Mahogany) Seed Extract on Indomethacin-induced Gastric Ulcers in Female Sprague-dawley Rats. Acta Medica Philippina. 3: 127–139.
Guevara, A. P., A. Apilado, H. Sakurai, M. Kozuka and H Tokuda. 1996. Anti-Inflammatory, Antimutagenic And Antitumor Promoting Activities of Mahogany Seeds, Swietenia macrophylla (Meliaceae). Philippine Journal of Science. 12: 5271–278.
Ardahe, S. S., M. A. Abdulla, S. A. Razak, F. A. Kadir and P. Hassandarvish. 2010. Gastroprotective Activity of Swietenia Mahagoni Seed Extract on Ethanol-Induced Gastric Mucosal Injury in Rats. World Academy of Science, Engineering and Technology. 67.
Wongkittipong, R., L. Prat, S. Damronglerd and C. Gourdon .2000. Solid-liquid extraction of andrographolide from plants-experimental study, kinetic reaction and model. Separation and Purification Technology. 40: 147–154.
Calabrese, C., S. H. Berman and J. G. Babish. 2000. A Phase I Trial of Andrographolide in HIV Positive Patients and Normal Volunteers. Phytotherapy Research. 14: 333–338.
Choudhury, B. R., S. J. Haque and M. K. Poddar. 1987. In Vivo and in Vitro Effects of Kalmegh (Andrographis paniculata) Extract and Andrographolide on Hepatic Microsomal Drug Metabolizing Enzymes. Planta Medica. 53: 135–140.
Rajani, M., N. Shrivastava and M. N. Ravishankara. 2000. A Rapid Method for Isolation of Andrographolide from Andrographis Paniculata Nees (Kalmegh). Pharmaceutical Biology. 38: 204–209.
Miliauskas, G., P. R. Venskutonis and T. A. van Beek. 2004. Screening of Radical Scavenging Activity of some Medicinal and Aromatic Plant Extracts. Food Chemistry. 85: 231–237.
Sahgal, G., S. Ramanathan, S. Sasidharan, M. N. Mordi, S. Ismail and S. M. Mansor. 2009. In Vitro Antioxidant and Xanthine Oxidase Inhibitory Activities of Methanolic Swietenia mahagoni Seed Extracts. Molecules. 14: 4476–4485.
Zarnowski, R. and Y. Suzuki. 2004. Expedient Soxhlet Extraction of Resorcinolic Lipids from Wheat Grains. Journal of Food Composition and Analysis. 17: 649–664.
Avanigadda, S. and M. Vangalapati. 2010. Experimental and Modelling Studies of Andrographolide Extraction from Andrographis Paniculata. International Journal of Chemical, Environmental and Pharmaceutical Research. 1(1): 32–36.
Majid, M. A., I. M. M. Rahman, M. A. H. Shipar, M. Helal Uddin and R. Chowdhury. 2004. Physico-Chemical Characterization, Antimicrobial Activity and Toxicity Analysis of Swietenia Mahagoni Seed Oil. International Journal of Agriculture and Biology. 6(2): 350–354.
Rodtjer, A., L. H. Skibsted and M. L. Andersen. 2006. Antioxidative and Prooxidative Effect of Extracts Made From Cherry Liqueur Pomace, Food Chemistry. 99: 6–14.
Pourmorad, F., S. J. Hosseinimehr and N. Shahabimajd. 2006. Antioxidant Activity, Phenol and Flavonoid Contents of Some Selected Iranian Medical Plants. African Journal of Bioechnology. 5(11): 1142–1145.
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