Modelling the Behaviour of Single Stage Splicing Language: A Yusof Goode Computational Approach

Authors

  • Wen Li Lim Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, 26300 UMP Gambang, Kuantan, Pahang
  • Yuhani Yusof Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, 26300 UMP Gambang, Kuantan, Pahang
  • Norhayati Rosli Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, 26300 UMP Gambang, Kuantan, Pahang
  • Mohammad Hassan Mudaber Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, 26300 UMP Gambang, Kuantan, Pahang

DOI:

https://doi.org/10.11113/jt.v73.3560

Keywords:

Yusof-Goode splicing system, splicing language, single stage limit language.

Abstract

Yusof-Goode (Y-G) splicing system is a formal characterization of the generative capacity of specified enzymatic activities acting on DNA molecules with new extension symbolization of representing rule. The output of Y-G splicing system can be categorized into three types of single stage splicing language namely active persistent, transient and inert persistent language. It is both money and time consuming to conduct laboratory experiments to determine the behaviour of splicing language. Hence, research has been conducted to predict the characteristic of single stage splicing language based on limit adjacency matrix computational modelling in order to optimize time and money. The utilization of software programming has been developed through Visual Basic Software for scientists to determine the behaviour of single stage splicing language as well as the number types of resulted DNA molecules restricted to at most two strings and two rules with one cutting site. The output from the program was found to match the outcomes of wet lab experiments.

Author Biographies

  • Yuhani Yusof, Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, 26300 UMP Gambang, Kuantan, Pahang
    FIST, Dr
  • Norhayati Rosli, Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, 26300 UMP Gambang, Kuantan, Pahang
    FIST, Dr
  • Mohammad Hassan Mudaber, Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, 26300 UMP Gambang, Kuantan, Pahang
    FIST

References

Head, T. 1987. Formal Language Theory and DNA: An Analysis of The Generative Capacity of Specific Recombinant Behaviors. Bulletin of Mathematical Biology. 49(6): 737–759.

Laun, T.E.G. 1999. Constants and Splicing Systems. State University of New York at Binghamton. Ph.D. Thesis.

Yusof, Y. 2012. DNA Splicing System Inspired by Bio Molecular Operations. Ph.D. Thesis, Universiti Teknologi Malaysia.

Goode, E. and Pixton, D. 2004. Splicing to The Limit. Lecture Notes in Computer Science. 2950: 189–201.

Lim, D.S.F. 2006. Splicing Systems and Language. MSc. Dissertation. Universiti Teknologi Malaysia.

Lim, W.L. and Yusof, Y. Modeling Limit Languages via Limit Adjacency Matrix and Yusof-Goode Approaches. 2014. Proceeding of International Conference of Mathematics, Engineering and Industrial Applications 2014 (ICoMEIA). in press.

Laun, E. and Reddy, K.J. 1999. Wet Splicing Systems. DIMACS Series in Discrete Mathematics and Theoretical Computer Science. 48: 73–83.

Visual Basic, Microsoft.NET, 2010

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Published

2015-02-09

Issue

Section

Science and Engineering

How to Cite

Modelling the Behaviour of Single Stage Splicing Language: A Yusof Goode Computational Approach. (2015). Jurnal Teknologi, 73(1). https://doi.org/10.11113/jt.v73.3560