Literature Survey of Protein Secondary Structure Prediction

Abstract

Dengan wujudnya projek jujukan DNA secara besar-besaran, teknik yang tepat untuk meramalkan struktur protein diperlukan. Masalah meramalkan struktur protein daripada jujukan DNA pada dasarnya masih belum dapat diselesaikan walaupun kajian intensif telah dilakukan selama lebih daripada tiga dekad. Dalam kertas kerja ini, teori asas struktur protein akan dibincangkan sebagai panduan umum bagi kajian peramalan struktur protein sekunder. Analisis jujukan terkini serta prinsi p yang digunakan dalam teknik-teknik tersebut akan diterangkan. Kata kunci: peramalan stuktur sekunder protein; rangkaian neural. In the wake of large-scale DNA sequencing projects, accurate tools are needed to predict protein structures. The problem of predicting protein structure from DNA sequence remains fundamentally unsolved even after more than three decades of intensive research. In this paper, fundamental theory of the protein structure of the protein structure will be presented as a general guide to protein secondary structure prediction research. An overview of the state-of-theart in sequence analysis and some princi ples of the methods invloved wil be described. Key words: protein secondary structure prediction;neural networks.