EFFECTS OF 900 MHZ RADIOFREQUENCY RADIATION ON THE RATS’ LIVER
DOI:
https://doi.org/10.11113/jt.v78.9078Keywords:
900 MHz mobile phone radiation, liver, histology, liver function testsAbstract
The goal of the study is to evaluate the liver function tests and histological alterations of the rats liver cells after exposure to mobile phone radiation. To perform the liver function test Aspartate transaminase (AST) U.V kinetic test kit produced by CYPRESS DIAGNOSTICS and spectrophotometer was used. Wistar rats (male, 5 week old, approximate body weight 30-40 g) (N = 12) were exposed to 900 MHz mobile phone radiation of Global System Mobile signal modulation (GSM), whole body average specific absorption rate SAR of 1.090W/kg. Twelve (12) male rats were used for the study divided into 3 groups of 4 rats each. Group B and Group C were exposed to 4 hours/day and 8 hours/day mobile phone radiation during calling mode for 2 months respectively while Group A served as control. There was significant reduction in total protein, globulin, while there was significantly increased in Glutamate Oxalacetate Transaminase (GOT), Alkaline Phosphatase (ALP), Albumin, total bilirubin in the rats (Group B and C) exposed to mobile phone radiation when compared to the control group but there was no histological alteration in the arrangement of cells in both control and exposed group. The results of this study suggest that, under the experimental conditions applied, repeated 900 MHz irradiation could modify liver functions.
References
Ellis, J. 2005. What is Electromagnetic Radiation? Retrieved on March, 4, 2012 from http://wisegeek.com/what-is-electromagnetic-radiation.htm.
Adey, W. R. 1993. Biological Effects of Electromagnetic Fields. Journal of Cell Biochemistry. 51(4): 410-416.
Laila, H. K., Sawsam, K. H. and Anisa, S. 2010. The Adverse Effect of Mobile Phone Radiation on some Visceral Organs. Research Journal of Medicine and Medical Sciences. 5(1): 95-99.
Khayyat, L. I. 2011. The Histopathological Effects of an Electromagnetic Field on the Kidney and Testis of Mice. Eurasia Journal of Bioscience. 5: 103-109.
Smialowicz, R. J., Weil, C. M., Marsh, M. R., Riddle, M. M., Rogers, R. R. and Reehnberg, B. F. 1981. Biological Effects of Rats Exposed to 970-MHZ Radiofrequency Radiation. Bioelectromagnetics. 2(3): 279-284.
Trosic, I., Pavicic, S., Milkovic-Kraus, M., Mladinic, M. and Zeljezic, D. 2011. Effect of Electromagnetic Radiofrequency Radiation on the Rats' Brain, Liver and Kidney Cells Measured By Comet Assay. Collegiums Antropologicum. 35(4): 1259-1264.
Belyaev, I., Koch, C., Terenius, O., Roxstrom-Lindquist, K., Malmgren, L., Sommer, W., Salford, L. and Persson, B. 2006. Exposure of Rat Brain To 915 MHz GSM Microwaves Induces Changes In Gene Expression But Not Double Stranded DNA Breaks or Effects on Chromatin Conformation. Bioelectromagnetics. 27: 295-306.
Beran, Y., Zulkuf, M., Suleyman, D., Dilek, U. and Murat, K. 2008. Extremely Low Frequency Magnetic Fields Cause Oxidative DNA Damage in rats. Int. J. Radiat. Biol. 84: 789-795.
Esmekaya, M., Ozer, C. and Seyhan, N. 2011. 900 Mhz Pulse-Modulated Radiofrequency Radiation Induces Oxidative Stress On Heart, Lung, Testis And Liver Tissues Gen. Physiol Biophys. 30(1): 84-89
Chang, S., Cho, J., Gil, H., Yang, J., Lee, E., Jeon, Y., Lee, Z., Lee, M., Hong, M., Ho-Son, T. and Hong, S. 2005. Genotoxicity Evaluation of Electromagnetic Fields Generated By 835-Mhz Mobile Phone Frequency Band. Eur J Cancer Prev. 14(2): 175-179.
Angelo, G., Minicuci, N., Paolo, R., Valerio, G. and Spiridione G. 2011. Mobile Phones and Head Tumours. The Discrepancies In Cause-Effect Relationships In The Epidemiological Studies - How Do They Arise? Environmental Health. 10: 59.
Xing-Jiu, H., Yang-Kyu, C., Hyung-Soon, I., Oktay, Y., Euisik, Y., and Hak-Sung, K. 2006. Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques. Sensors (Basel). 6(7): 756-782.
Shalaka, D., Chandanam, K. and Chandrasekhar, K. B. 2015. Ethanol Induced Hepatoprotective Activity of Boswellia ovalifoliolata. Journal of Academia and Industrial Research (JAIR). 3(8): 365-370.
Iweala, E., Uhegbu, F. and Adesanoye, O. 2013. Biochemical Effects of Leaf Extracts of Gongronema Latifolium and Selenium Supplementation In Alloxan Induced Diabetic Rats. Journal of Pharmacognosy and Phytotherapy. 5(5): 91-97.
Aliyu, R., Adebayo, A. H., Gatsing, D. and Garba, I. H. 2007. The Effects of Ethanolic Leaf Extract of Commiphora Africana (Burseraceae) on Rat Liver and Kidney Functions. Journal of Pharmacology and Toxicology. 2: 373-379.
Klein, S. 2011. Protein-energy malnutrition. In Goldman L, Schafer AI (eds.) Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier. 222.
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