FREE RADICAL SCAVENGING ACTIVITY OF SELECTED SEA CUCUMBER SPECIES FROM MATARAM-LOMBOK, INDONESIA

Authors

  • Ratih Pangestuti Research Center for Oceanography, Indonesian Institute of Sciences, Jl. Pasir Putih 1, Ancol Timur, Jakarta Utara, 14430, Republic of Indonesia
  • Tutik Murniasih Research Center for Oceanography, Indonesian Institute of Sciences, Jl. Pasir Putih 1, Ancol Timur, Jakarta Utara, 14430, Republic of Indonesia
  • Masteria Yunovilsa Putra Research Center for Oceanography, Indonesian Institute of Sciences, Jl. Pasir Putih 1, Ancol Timur, Jakarta Utara, 14430, Republic of Indonesia
  • Abdullah Rasyid Research Center for Oceanography, Indonesian Institute of Sciences, Jl. Pasir Putih 1, Ancol Timur, Jakarta Utara, 14430, Republic of Indonesia
  • Joko Tri Wibowo Research Center for Oceanography, Indonesian Institute of Sciences, Jl. Pasir Putih 1, Ancol Timur, Jakarta Utara, 14430, Republic of Indonesia
  • Ardi Ardiansyah Research Center for Oceanography, Indonesian Institute of Sciences, Jl. Pasir Putih 1, Ancol Timur, Jakarta Utara, 14430, Republic of Indonesia
  • Febriana Untari Research Center for Oceanography, Indonesian Institute of Sciences, Jl. Pasir Putih 1, Ancol Timur, Jakarta Utara, 14430, Republic of Indonesia

DOI:

https://doi.org/10.11113/jt.v78.8202

Keywords:

Mataram, Lombok, radical, scavenging, sea cucumber

Abstract

Sea cucumber is an important food and remedies in Eastern hemisphere. However, less study have been performed to identify health benefit effects of sea cucumber from tropical region. In this study, radical scavenging activity of sea cucumber from Mataram - Lombok [Holothuria leucospilota, Holothuria atra, Holothuria fuscocinerea, and Holothuria excellens] were studied. Compared to other species at concentration of 0.1 mg mL–1, H. atra extract showed strongest scavenging activity in 2,2-Diphenyl-1-picrylhydrazyl (DPPH) (13.14 ± 2.17) % and absorbance value of β-carotene linoleic acid model at 180 min was (3.32 ± 1,12). H. atra extract were further fractionated, and ethyl acetate fractions (fr. 6) significantly inhibit radical activity at 180 min with the absorbance value of 2.84 ± 0.2. It can be concluded that H. atra is an important sea cucumber from tropical region.

References

Pangestuti, R., B. Ryu, S. Himaya, and S. K. Kim. 2013. Optimization of Hydrolysis Conditions, Isolation, and Identification of Neuroprotective Peptides Derived from Seahorse Hippocampus trimaculatus. Amino Acids. 45(2): 369–381.

Bahrami, Y., W. Zhang, and C. Franco. 2014. Discovery of Novel Saponins from the Viscera of the Sea Cucumber Holothuria lessoni. Marine Drugs.12(5): 2633–2667.

Masella, R., R. Di Benedetto, R. Vari, C. Filesi, and C. Giovannini. 2005. Novel Mechanisms of Natural Antioxidant Compounds in Biological Systems: Involvement of Glutathione and Glutathione-related Enzymes. The Journal of Nutritional Biochemistry. 16(10): 577–586.

Lovell, M. A., and W. R. Markesbery. 2007. Oxidative DNA Damage in Mild Cognitive Impairment and Late-stage Alzheimer's Disease. Nucleic Acids Research. 35(22): 7497–7504.

Mendis, E., N. Rajapakse, and S. K. Kim. 2005. Antioxidant Properties of a Radical-cavenging Peptide Purified from Enzymatically Prepared Fish Skin Gelatin Hydrolysate. Journal of Agricultural and Food Chemistry. 53(3): 581–587.

Pangestuti, R., and S. K. Kim. 2013. Marine-derived Bioactive Materials for Neuroprotection. Food Science and Biotechnology. 22(5): 1175–1186.

Himaya, S., B. Ryu, D. H. Ngo, and S. K. Kim. 2012. A Peptide Isolated From Japanese Flounder Skin Gelatin Protects Against Cellular Oxidative Damage. Journal of Agricultural and Food Chemistry. 60(36): 9112–9119.

Zhao, Y., B. Li, Z. Liu, S. Dong, X. Zhao, and M. Zeng. 2007. Antihypertensive Effect and Purification of an ACE Inhibitory Peptide from Sea Cucumber Gelatin Hydrolysate. Process Biochemistry. 42(12): 1586–1591.

Mamelona, J., É. Pelletier, K. Girard-Lalancette, J. Legault, S. Karboune, and S. Kermasha. 2007. Quantification of Phenolic Contents and Antioxidant Capacity of Atlantic Sea Cucumber, Cucumaria frondosa. Food Chemistry. 104(3): 1040–1047.

Althunibat, O. Y., R. B. Hashim, M. Taher, J. M. Daud; M. A. Ikeda, and B. Zali. 2009. In Vitro Antioxidant and Antiproliferative Activities of Three Malaysian Sea Cucumber Species. European Journal of Scientific Research. 37(3): 376–387.

Himaya, S., B. Ryu, Z. J. Qian, Y. Li, and S. K. Kim. 2011. 1-(5-bromo-2-hydroxy-4-methoxyphenyl) Ethanone [SE1] Suppresses Pro-inflammatory Responses by Blocking NF-κB and MAPK Signaling Pathways in Activated Microglia. European Journal of Pharmacology. 670(2): 608–616.

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Published

2016-04-12

How to Cite

FREE RADICAL SCAVENGING ACTIVITY OF SELECTED SEA CUCUMBER SPECIES FROM MATARAM-LOMBOK, INDONESIA. (2016). Jurnal Teknologi, 78(4-2). https://doi.org/10.11113/jt.v78.8202