SIMULTANEOUS ELECTROCHEMICAL DETECTION OF ASCORBIC ACID, DOPAMINE, AND URIC ACID AT MAGNETIC NANOPARTICLES/REDUCED GRAPHENE OXIDE MODIFIED ELECTRODE

Authors

  • Azleen Rashidah Mohd Rosli Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030 Kuala Terengganu, Malaysia
  • Farhanini Yusoff Faculty of Science and Marine Environment https://orcid.org/0000-0002-1838-9451
  • Saw Hong Loh Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030 Kuala Terengganu, Malaysia
  • Hanis Mohd Yusoff Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030 Kuala Terengganu, Malaysia
  • Muhammad Mahadi Abdul Jamil Faculty of Electrical and Electronic Engineering, University Tun Hussein Onn Malaysia, Batu Pahat, 86400 Johor, Malaysia
  • Shazrul Hasry Shamsudin SGS Malaysia Sdn. Bhd., Lot 3 & Lot, 4, Persiaran Jubli Perak, Seksyen 22, 40300 Shah Alam, Selangor, Malaysia

DOI:

https://doi.org/10.11113/jurnalteknologi.v83.15161

Keywords:

Ascorbic acid, dopamine, grapheme, magnetic, uric acid

Abstract

A magnetic nanoparticles/reduced graphene oxide modified glassy carbon electrode (MNP/rGO/GCE) was fabricated via one-step facile synthesis route for the simultaneous determination of ascorbic acid (AA), dopamine (DA), along with uric acid (UA). A series of diseases and disorders has been associated with irregular levels of these respective analytes, thus early detection is highly crucial. Physical and electrochemical characterization of the modified electrode was conducted by using Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR) analysis, X-Ray Diffraction (XRD) analysis and Brauneur-Emmet-Teller (BET), Cyclic Voltammetry (CV) and Electron Impedance Spectroscopy (EIS). The results obtained confirmed the formation of MNP/rGO composite. Differential pulse voltammetry (DPV) of MNP/rGO/GCE displays three well-defined peaks which associated to AA, DA and UA, respectively. The response towards DA is linear in the concentration range of 15 nM to 100 µM with a detection limit of 0.19 nM while a response to AA and UA is also linear in the concentration range of 10 µM to 100 µM with a limit of detection 0.22 µM and 45 nM respectively. The proposed modified electrode offers a good response towards simultaneous detection of three different electroactive species with excellent electron transfer rate, great capacitance and ideal diffusive control behavior.

Published

2021-04-01

Issue

Section

Science and Engineering